Selective Intra-Arterial Fibrinolysis of Acute Central Retinal Artery Occlusion

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Selective Intra-Arterial Fibrinolysis of Acute Central Retinal Artery Occlusion

Background and Purpose—Occlusion of the central retinal artery (CRAO) causes a sudden decrease of monocular vision. Because early restoration of blood flow may improve outcome, we attempted to treat CRAO with selective intra-arterial fibrinolysis. Methods—Intra-arterial fibrinolysis was performed within 6 hours after symptom onset in 17 patients with thromboembolic CRAO. Symptoms were painless,...

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Selective intraarterial fibrinolysis of acute central retinal artery occlusion.

PURPOSE To evaluate the outcome of our patients with central retinal artery occlusion after local fibrinolysis and to compare these data with results reported in the literature. MATERIAL AND METHODS Over a period of 7 years, 22 patients (11 male, 11 female, mean age 64.6 +/- 12.1 years) were treated with super-selective local fibrinolysis. In 1 case, treatment was carried out via the maxillar...

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Intra-Arterial Fibrinolysis Not Recommended for Central Retinal Artery Occlusion Central Retinal Artery Occlusion: Local Intra-Arterial Fibrinolysis Versus Conservative Treatment, A Multicenter Randomized Trial

Objective: To evaluate the safety and efficacy of local intra-arterial fibrinolysis with tissue plasminogen activator (tPA) in the management of patients with central retinal artery occlusion. Design: Prospective randomized multicenter clinical trial (the European Assessment Group for Lysis in the Eye study). Methods: 9 centers in Austria and Germany recruited 84 patients with central retinal a...

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Local intra-arterial fibrinolysis for acute occlusion of the central retinal artery: a meta-analysis of the published data.

BACKGROUND/AIM Central retinal artery occlusion (CRAO) is typically associated with a poor visual outcome. Several favourable reports of local intra-arterial fibrinolysis (LIF), which involves the superselective administration of a thrombolytic agent directly into the ophthalmic artery, have appeared in the recent literature. The aim of this study was to critically appraise these studies in a c...

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Comparison of intra-arterial thrombolysis with conventional treatment in patients with acute central retinal artery occlusion.

BACKGROUND Several case series and a recent meta-analysis indicate that intra-arterial thrombolysis (IAT) is effective for the treatment of acute central retinal artery occlusion (CRAO). METHODS A total of 37 patients with acute monocular blindness because of unilateral thromboembolic CRAO were treated with IAT using urokinase within six hours of the onset of symptoms. Visual outcome was comp...

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ژورنال

عنوان ژورنال: Stroke

سال: 1998

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.29.10.2076